Sourav Pan An Atomic Force Microscope, often known as an AFM, is a highly advanced tool that gives researchers the ability to view surfaces on a nanoscale scale. In contrast to conventional optical microscopes, which are constrained by the diffraction of light, atomic force microscopes (AFMs) are able to attain resolutions that are as low as fractions … Read more
The darkfield microscope dates back to the early 19th century with some of the developments in optical microscopy. It was then that scientists started conducting experiments on different illumination techniques in a quest to maximize contrast for observing transparent and fragile specimens. Toward the late 1800s, the darkfield technique became quite popular, especially when live … Read more
Fluorescence microscopes—have you ever wondered how scientists capture such vivid, glowing images of cells, tissues, or even bacteria? This is where fluorescence microscopes come into play, using fluorescence and, at times, phosphorescence to reveal the hidden intricacies within both organic and inorganic materials. It is like magic, but it is based on the science of … Read more
The oil immersion technique is a method used in microbiology to increase the resolution of a microscope when examining specimens at high magnification. By applying a special oil (usually immersion oil) between the lens and the slide, it enhances the clarity of the image. Why is oil necessary? It’s all about improving light transmission. Without … Read more
What is transmission electron microscope? Transmission Electron Microscope (TEM) – A TEM is a high-resolution microscope that uses a beam of electrons to pass through a thin sample, creating detailed images of the internal structure at the atomic or molecular level. It is used in material science, biology, and nanotechnology to examine ultrastructure. This is … Read more
A Scanning Electron Microscope is a game-changer in the world of imaging. Imagine the ability to zoom in on an object so closely that even the tiniest details come alive in stunning clarity. That is what SEM does. But how does it work? Let’s break it down. An SEM uses a beam of electrons instead … Read more
Phase-contrast microscopy transforms subtle variations in refractive index and cell density into noticeable changes in light intensity, allowing researchers to study living cells. The microscope is a microscope for viewing cell culture and live cells. Living cells can be seen unstained. Unstained specimens have absorbed no light, so it produces very small differences in the … Read more
The Confocal Microscope, like most advanced imaging systems, can be distinguished by its use of laser light to generate high-resolution images at varying depths within samples. These microscopes, which operate on the principle of confocal laser scanning microscopy (CLSM), then utilize a focused laser beam to scan specimens and detect fluorescence emissions at different depths. … Read more
What is a Dissecting microscope (Stereo microscope)? Dissecting microscope (stereo microscope), It’s typically used to look at small things or for dissections or soldering, activities that need close-up viewing. Dissecting microscopes generally offer low magnification levels (approximately 4x to 50x) and have a relatively large working distance so that the object being viewed may be … Read more
Picture yourself looking into a universe so small it cannot be seen by the eyes; microscopes open that galaxy. These clever gadgets make things and samples appear bigger, showing us a lot of complex, detailed stuff that wouldn’t be perceptible to us otherwise. Be it a scientist scoping out cells, or a student awing over … Read more